USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: VDAC1_HUMAN USC-OGP 2-DE database:  VDAC1_HUMAN VDAC1_HUMAN General information about the entry View entry in simple text format Entry name VDAC1_HUMAN Primary accession number P21796 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Voltage-dependent anion-selective channel protein 1; Short=VDAC-1; Short=hVDAC1; AltName: Full=Outer mitochondrial membrane protein porin 1; AltName: Full=Plasmalemmal porin; AltName: Full=Porin 31HL; AltName: Full=Porin 31HM;. Gene name Name=VDAC1 Synonyms=VDAC Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0990: pI=8.20; Mw=28404 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1290: pI=6.61; Mw=24887 Cross-references UniProtKB/Swiss-Prot P21796; VDAC1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name VDAC1_HUMAN Primary accession number P21796 Secondary accession number(s) B3KVK4 D3DQ93 Q5FVE7 Q9UIQ5 Q9UPL0 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 193) Name and origin of the protein Description RecName: Full=Voltage-dependent anion-selective channel protein 1; Short=VDAC-1; Short=hVDAC1; AltName: Full=Outer mitochondrial membrane protein porin 1; AltName: Full=Plasmalemmal porin; AltName: Full=Porin 31HL; AltName: Full=Porin 31HM; Gene name Name=VDAC1 Synonyms=VDAC Encoded on Name=VDAC1; Synonyms=VDAC Keywords 3D-structure; Acetylation; Apoptosis; Cell membrane; Complete proteome; Direct protein sequencing; Host-virus interaction; Ion transport; Isopeptide bond; Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein; Porin; Reference proteome; Transmembrane; Transmembrane beta strand; Transport; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL L06132; AAA61272.1; -; mRNA EMBL AJ250032; CAB58127.1; -; Genomic_DNA EMBL AJ250033; CAB58127.1; JOINED; Genomic_DNA EMBL AJ250034; CAB58127.1; JOINED; Genomic_DNA EMBL AJ250035; CAB58127.1; JOINED; Genomic_DNA EMBL AJ250036; CAB58127.1; JOINED; Genomic_DNA EMBL AJ250037; CAB58127.1; JOINED; Genomic_DNA EMBL AJ250038; CAB58127.1; JOINED; Genomic_DNA EMBL AJ250039; CAB58127.1; JOINED; Genomic_DNA EMBL AF151097; AAD54939.1; -; Genomic_DNA EMBL AF151093; AAD54939.1; JOINED; Genomic_DNA EMBL AF151094; AAD54939.1; JOINED; Genomic_DNA EMBL AF151095; AAD54939.1; JOINED; Genomic_DNA EMBL AF151096; AAD54939.1; JOINED; Genomic_DNA EMBL AC005200; AAC24723.1; -; Genomic_DNA EMBL AK122953; BAG53816.1; -; mRNA EMBL AC008608; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471062; EAW62281.1; -; Genomic_DNA EMBL CH471062; EAW62282.1; -; Genomic_DNA EMBL CH471062; EAW62283.1; -; Genomic_DNA EMBL CH471062; EAW62285.1; -; Genomic_DNA EMBL CH471062; EAW62286.1; -; Genomic_DNA EMBL BC008482; AAH08482.1; -; mRNA EMBL BC071168; AAH71168.1; -; mRNA EMBL BC090042; AAH90042.1; -; mRNA CCDS CCDS4168.1; -; . PIR A44422; MMHUP3; . RefSeq NP_003365.1; NM_003374.2; . RefSeq XP_005272132.1; XM_005272075.3; . RefSeq XP_016865310.1; XM_017009821.1; . RefSeq XP_016865311.1; XM_017009822.1; . RefSeq XP_016865312.1; XM_017009823.1; . UniGene Hs.519320; -; . PDB 2JK4; X-ray; 4.10 A; A=2-283 PDB 2K4T; NMR; -; A=1-283 PDB 5JDP; NMR; -; A=2-283 PDBsum 2JK4; -; . PDBsum 2K4T; -; . PDBsum 5JDP; -; . ProteinModelPortal P21796; -; . SMR P21796; -; . BioGrid 113259; 136; . DIP DIP-32862N; -; . IntAct P21796; 45; . MINT MINT-5002499; -; . STRING 9606.ENSP00000265333; -; . DrugBank DB01375; Aluminium monostearate; . iPTMnet P21796; -; . PhosphoSitePlus P21796; -; . SwissPalm P21796; -; . BioMuta VDAC1; -; . DMDM 130683; -; . DOSAC-COBS-2DPAGE P21796; -; . OGP P21796; -; . REPRODUCTION-2DPAGE IPI00216308; -; . REPRODUCTION-2DPAGE P21796; -; . UCD-2DPAGE P21796; -; . EPD P21796; -; . MaxQB P21796; -; . PaxDb P21796; -; . PeptideAtlas P21796; -; . PRIDE P21796; -; . TopDownProteomics P21796; -; . DNASU 7416; -; . Ensembl ENST00000265333; ENSP00000265333; ENSG00000213585; . Ensembl ENST00000395044; ENSP00000378484; ENSG00000213585; . Ensembl ENST00000395047; ENSP00000378487; ENSG00000213585; . GeneID 7416; -; . KEGG hsa:7416; -; . UCSC uc003kyp.3; human; . CTD 7416; -; . DisGeNET 7416; -; . GeneCards VDAC1; -; . H-InvDB HIX0056260; -; . HGNC HGNC:12669; VDAC1; . HPA CAB005885; -; . HPA HPA030780; -; . MIM 604492; gene+phenotype; . neXtProt NX_P21796; -; . OpenTargets ENSG00000213585; -; . PharmGKB PA37292; -; . eggNOG KOG3126; Eukaryota; . eggNOG ENOG410ZBK1; LUCA; . GeneTree ENSGT00390000011336; -; . HOGENOM HOG000188277; -; . HOVERGEN HBG054036; -; . InParanoid P21796; -; . KO K05862; -; . OMA YGLMFTE; -; . OrthoDB EOG091G0F0O; -; . PhylomeDB P21796; -; . TreeFam TF315091; -; . Reactome R-HSA-1268020; Mitochondrial protein import; . Reactome R-HSA-5205685; Pink/Parkin Mediated Mitophagy; . Reactome R-HSA-5689880; Ub-specific processing proteases; . SIGNOR P21796; -; . ChiTaRS VDAC1; human; . EvolutionaryTrace P21796; -; . GeneWiki VDAC1; -; . GenomeRNAi 7416; -; . PRO PR:P21796; -; . Proteomes UP000005640; Chromosome 5; . Bgee ENSG00000213585; -; . CleanEx HS_VDAC1; -; . ExpressionAtlas P21796; baseline and differential; . Genevisible P21796; HS; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016020; C:membrane; ISS:UniProtKB; . GO GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell; . GO GO:0005743; C:mitochondrial inner membrane; IEA:Ensembl; . GO GO:0042645; C:mitochondrial nucleoid; IDA:BHF-UCL; . GO GO:0005741; C:mitochondrial outer membrane; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IDA:UniProtKB; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; IDA:UniProtKB; . GO GO:0046930; C:pore complex; TAS:HGNC; . GO GO:0008021; C:synaptic vesicle; IEA:Ensembl; . GO GO:0044325; F:ion channel binding; IPI:UniProtKB; . GO GO:0015288; F:porin activity; IEA:UniProtKB-KW; . GO GO:0019901; F:protein kinase binding; IPI:ParkinsonsUK-UCL; . GO GO:0008308; F:voltage-gated anion channel activity; IDA:UniProtKB; . GO GO:0006820; P:anion transport; IDA:UniProtKB; . GO GO:0006915; P:apoptotic process; IDA:UniProtKB; . GO GO:0001662; P:behavioral fear response; IEA:Ensembl; . GO GO:0030855; P:epithelial cell differentiation; IEP:UniProtKB; . GO GO:0007612; P:learning; IEA:Ensembl; . GO GO:0016236; P:macroautophagy; TAS:Reactome; . GO GO:0006851; P:mitochondrial calcium ion transport; IEA:Ensembl; . GO GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IEA:Ensembl; . GO GO:0007270; P:neuron-neuron synaptic transmission; IEA:Ensembl; . GO GO:1903146; P:regulation of mitophagy; NAS:ParkinsonsUK-UCL; . GO GO:0016032; P:viral process; IEA:UniProtKB-KW; . Gene3D 2.40.160.10; -; 1; . InterPro IPR023614; Porin_dom; . InterPro IPR001925; Porin_Euk; . InterPro IPR027246; Porin_Euk/Tom40; . InterPro IPR030270; VDAC1; . PANTHER PTHR11743:SF37; PTHR11743:SF37; 1; . Pfam PF01459; Porin_3; 1; . PRINTS PR00185; EUKARYTPORIN; . PROSITE PS00558; EUKARYOTIC_PORIN; 1; .

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